No evidence of homocysteine or hydrogen peroxide influence at the crayfish neuromuscular junction

Abstract

Due to the differences between crayfish and mammals, we researched how homocysteine (HCY) and hydrogen peroxide (H₂O₂) affect the crayfish neuromuscular junction (NMJ). We hypothesized that H₂O₂ would decrease synaptic activity at the crayfish NMJ, while HCY would enhance this inhibitory effect. We used electrophysiology to examine how the NMJ was influenced by HCY and H₂O₂. We concluded that there is no evidence of HCY or H₂O₂ influence on synaptic activity at the crayfish NMJ.