Glutathione and Coenzyme Q10 Show No Additive Neuroprotective Effect at the Neuromuscular Junction of Crayfish

  • Alex Ross Grinnell College
  • Harper Smith Grinnell College

Abstract

This study examined the effects of antioxidants Coenzyme Q10 and Glutathione at the neuromuscular junction of crayfish. We hypothesized that a solution containing both Coenzyme Q10 and Glutathione would show higher EJPs then each of the antioxidants independently. Microelectrodes were inserted into the superficial extensor muscles of a crayfish tail to record the excitatory junction potential (EJP) of crayfish exposed to three different combinations of antioxidants in response to a neurodegenerative substance (hydrogen peroxide). We found that there was no significant additive effect when Coenzyme Q10 and Glutathione are applied together on preventing neuromuscular degeneration

Published
2017-12-14
How to Cite
ROSS, Alex; SMITH, Harper. Glutathione and Coenzyme Q10 Show No Additive Neuroprotective Effect at the Neuromuscular Junction of Crayfish. Pioneering Neuroscience, [S.l.], v. 16, p. 29-32, dec. 2017. Available at: <https://ojs.grinnell.edu/index.php/pnsj/article/view/446>. Date accessed: 25 sep. 2018.
Section
Articles