TY  - JOUR
AU  - Hall, Pelle
AU  - Brooks, Colin
AU  - Marks, Jordan
AU  - Kaiser-Nyman, Chris
PY  - 2010
TI  -  Octopamine Operates Through the cGMP Pathway at the Crayfish Neuromuscular Junction
JF  - Pioneering Neuroscience; Vol 11 (2010)
KW  - 
N2  - We studied the neurohormone octopamine, attempting to determine if the cGMP pathway is involved in the modulation of synaptic transmission by octopamine in  Procambarus clarkii  muscle cells. We applied a soluble guanylyl cyclase inhibitor (ODQ) along with octopamine in different combinations to the prepared crayfish and measured excitatory postsynaptic potential (EPSP) amplitudes of extensor muscles of crayfish. Our results support our hypothesis that cGMP is involved in the octopamine pathway, as application of ODQ decreased the effect of octopamine on EPSP amplitudes.
UR  - https://ojs.grinnell.edu/index.php/pnsj/article/view/67